In the mid 1980s, researchers at St. Louis University made two groundbreaking discoveries that led to the implication that the brain has its own endogenous receptors for cannabinoids. G-protein coupled CB1 and CB2 receptors were confirmed shortly thereafter, and a new biological system was announced: the endocannabinoid system (ECS).
Research has made widely known our endocannabinoid system (ECS); to many, this revelation primes several questions: “If I’ve always had an ECS that responds to specific ligands found in certain plants, what has it been up to for all this time?” Since it’s complementary to the nervous system, is there a healthy median baseline to be aware of? What can happen if mine over- or under-performs? These are all valid questions since a state of homeostasis depends upon optimum balance in the body.